Verification Services for NAM Testing

This page explains how UC Davis approaches NAM testing verification so researchers can assess whether a NAM test faithfully reflects in vivo biology.

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Use our Method Verification services to assess the foundational accuracy and reliability of your Novel Alternative Methodology (NAM). Whether you are developing a new NAM, optimizing an existing one, or troubleshooting unexpected results, these services are crucial for assessing your NAM's accuracy, validity, and predictability, giving you confidence in the extent to which it represents an in vivo biological system.

We achieve this by working with you to design a tailored testing plan that meets your unique needs and specific NAM characteristics. Our process utilizes a suite of advanced testing and phenotyping platforms and analytical procedures to evaluate your NAM's research outputs. This often involves customizing comparisons against relevant in vivo models that represent the biological or pathophysiological system(s) your NAM intends to recapitulate.

Our staff will assist you in selecting an existing or designing and developing a new in vivo model (e.g., gene knockout, genetically humanized, PDX), ensuring it appropriately reflects your NAM. All data generated from this service is wholly owned by the requesting investigator, providing robust, actionable insights for immediate optimization, ensuring your NAM is refined to meet your precise scientific objectives.

Questions about demonstrating the foundational accuracy of your method? Contact us.

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